Vega ZZ TOP ROCKS!! Molecular Modeling Tutorial

Whatta sweet program - up there with PYMOL

The integration of ESCHER NG adds Docking capability (the ability to toss a 3D protein file (eg PDB and test its compatability with another protein or a small ligand. To take advantage of this tool you may choose to first apply the MOPAC6 - this will perform quantum mechanic functions on selected regions - by selecting pockets from a 3d server like the Leeds Bioinformatic Pocket Finder You can adjust the selected pocket regions from the resulting pdb file to better understand the docking potentials...

In our example we will look at how the tetrahydrocannabinolic acid synthase [Cannabis sativa (hemp)] molecule you can download the pdb file from the National Institute of Health

change atom style isis chime

change atom style isis chime
Originally uploaded by phunktion.

A sweet tutorial is now available on Flickr.com that'll show you how to design a small 50s ish atom molecule and clean it up to get into Rasmol .mol format for 3d viewing pleasure - stay tuned in for a groovy Pymol tutorial soon to follow.

To follow this tutorial you'll need a copy of MDL Chime - a free chemistry modeller / design tool provided by Elsevier MDL

Classy Lady Advises "Get yo fat ass in a lap band biatch!!"

Pageant Coaching at Classy Lady - get your fat ass in a lap band!

***revision*** ok so it was a banner ad - still it's a classic, and there are two of them there from lap-band surgeons in Mexico
This is lap-band lab-laugh-spictacular Check it out - you can't make this up

This one has got to be one of the most epic sites to date - straight up - are you a fat ass? ok, go to our Mexican Dr. named Pedro and have him hove a ring around your fat stomach and quit eating! :)
Dr. Pedro Kuri at your convenience - and a mere hop skip and no malpractice jump across the border.... Voyla! Fighting your gargantuan gluttony is a disease, and Dr. Pedro has the cure.


What part of "Stop eating, you fat bastard" don't you understand - course the doc's jus' doin' his job - repeat business is good business....



ah well.

details

details
Originally uploaded by funkydude.

The details - it's all in them, that and the big stuff - it's all in that too

Cannabidiol-3d - Part II of "How to arrest Brown People" WAABoBM

cannabidiol-3d - part II of "How to arrest Brown People"
Originally uploaded by funkydude.

Arresting brown people. A national pastime here in America, land of the.... something. Beautiful land. America. Wouldn't leave it unless absolutely necessary. On the other hand, when are we gonna stop aresting brown people for carrying around atoms of a different arrangement. It can't possibly matter much. A few errant electrons... if things keep going along brown mothers will simply give birth to their offspring in prison. Cradle to grave in the goo-goo-ga-ga-logs. Biosynthesis of Cannbinoids. Prolly shoulda read this one before that last post on Olivetol... Olivetolic Acid is the reactant species, and clearly more rawkus than mere Olivetol.

Hoooweeeee!

Makes my blood boil a bit thinking about it. The question becomes whether those misplaced carbons + hydrogens (ergo acid) would constitute a felony "charge" - please forgive the pun.... or don't... or if the olivetol, meke and neutral might be free! Free at last!!!! Who'da thunk it.


In 1990, of the 739,960 sentenced prisoners in Federal and State prisons, 370,400 were African-American. According to a 2004 report, "At yearend 2003 black males (586,300) outnumbered white males (454,300) and Hispanic males (251,900) among inmates with sentences of more than 1 year (table 11). More than 44% of all sentenced male inmates were black."

So the WoA (War of Atoms) can now officially be dubbed The WAABoBM! (War Against All Brownish or Blackish Men)

Tunisia DEM in 3D using Microdem 8.01 alpha

tunisia-3d-microdem
Originally uploaded by funkydude.

This is a 3D pic of Tunisia near where the 26th Infantry took off from during WWII on their Jihad against Hitler. Peter Guth, sometimes known as "The General" in GIS circles developed MicroDEM or Terraserver II it is closed source, but its implementation of OpenGL is awesome. ROCK ON PETER GUTH, ROCK ON BLUESPADERS!

OLIVETOL

OLIVETOL
Originally uploaded by funkydude.

This is Olivetol, aka C11-H16-02. Olivetol is of the Terpenoid series - many of the etherial wonders of the world are of this series Terpene Biosynthesis is a good review of this process. Olivetol is the precrusor of cannabidiol which is the precursor of delta nine tetrahydrocannabinol, THC. These are the atoms that the US Government believes it is fighting in its "War on Drugs" aka "War on Atoms." Allegedly there were some electrons that were spinning without proper identification... however due to several equations it has been determined that their precise nature will never ever ever be determined... ergo this is a lost cause... this makes our foray into Vietnam look like a methodical act of foresite. Next to the WoA... well there's nothing coming to mind right now to compare it to. It's too stupid. In a league of its own ignorance.